| | 1 | 1 |  Sarah Hernandez Terra Jackson  James Muscart Dylan Scott | U40 | 00:54:23 | |
| | 2 | 2 | Megan Voigt Joey Quinones Abigail Leone Matthew Gelchion | U40 | 01:03:10 | |
| | 3 | 3 | Shaun Baluyot Raymond Melencio Larissa Reinkensmeyer Paula Gutiérrez | U40 | 01:06:09 | |
| | 4 | 1 | Stephanie Ricedorf Ben Zeeb Jen Stagnoli Brian Cunningham | 40+ | 01:08:37 | |
| | 5 | 4 | Ashley Etue Carina Burdick Karl Heuchert Michael Jeng | U40 | 01:11:11 | |
| | 6 | 2 | Vitaly Slabada Todd Loesch Kerry Hughes Lacy Marinenko | 40+ | 01:11:34 | |
| | 7 | 5 |  Thomas Schuler Miller Gisela Miranda Difini Brenner Swenson Veronica Leynes-Zwirn | U40 | 01:14:12 | |
| | 8 | 6 | Keyshlamarie Pérez Muriel James Wright Janina Dunklau Jake Schoolmeesters | U40 | 01:15:42 | |
| | 9 | 3 | Nancy Witt Mike Childers Ernest Sherman Danielle Schiff | 40+ | 01:17:00 | |
| | 10 | 7 | Ariel Brenits  Prabhath Kiran Atmakuri Jenny Scherer Stefan Hench | U40 | 01:20:33 | |
| | 11 | 8 | Ali Barzyk Tammy Nguyen Jordan Harris David Webster | U40 | 01:21:21 | |
| | 12 | 9 | Colin Parker Chelsey Bazuro Daniel Castro Andreina Damiano | U40 | 01:21:43 | |
| | 13 | 10 |  Colm Buckley Emma Roberts Maria Rueda Timothy Vella | U40 | 01:26:23 | |
| | 14 | 11 | Myshawn Smith Dionis Harvey Mekeya Brown Kendall Patterson | U40 | 01:30:16 | |
| | 15 | 4 | Tiffany Agamaite Jamie Enderby Zachary Enderby Brian Reindl | 40+ | 02:08:30 | |
